Question 87. Question :
The elderly are at high risk of ADRs due to:
Having greater muscle mass than younger adults, leading to higher volume of distribution
The extensive studies that have been conducted on drug safety in this age group
The blood-brain barrier being less permeable, requiring higher doses to achieve therapeutic effect
Age-related decrease in renal function
Question 88. Question :
Jim presents with fungal infection of two of his toenails (onychomycosis). Treatment for fungal infections of the nail includes:
Question 89. Question :
Directly bind to a receptor in the pancreatic beta cell.
Have been approved for monotherapy.
Speed gastric emptying to decrease appetite.
Can be given orally once daily.
Question 90. Question :
Prophylactic use of bisphosphonates is recommended for patients with early osteopenia related to long-term use of which of the following drugs?
Selective estrogen-receptor modulators
Question 91. Question :
Inadequate vitamin D intake can contribute to the development of osteoporosis by:
Increasing calcitonin production
Increasing calcium absorption from the intestine
Altering calcium metabolism
Stimulating bone formation
Question 92. Question :
Which of the following statements is true about age and pain?
Use of drugs that depend heavily on the renal system for excretion may require dosage adjustments in very young children.
Among the NSAIDs, indomethacin is the preferred drug because of lower adverse effects profiles than other NSAIDs.
Older adults who have dementia probably do not experience much pain due to loss of pain receptors in the brain.
Acetaminophen is especially useful in both children and adults because it has no effect on platelets and has fewer adverse effects than NSAIDs.
Question 93. Question :
Selective estrogen receptor modifiers (SERMs) treat osteoporosis by selectively:
Inhibiting magnesium resorption in the kidneys
Increasing calcium absorption from the gastrointestinal (GI) tract
Acting on the bone to inhibit osteoblast activity
Selectively acting on the estrogen receptors in the bone