Reflect on a case from your past clinical experiences and consider how a patient’s pharmacokinetic and pharmacodynamic processes may alter his or her response to a drug.

To Prepare

· Review the Resources for this module and consider the principles of pharmacokinetics and pharmacodynamics.

· Reflect on your experiences, observations, and/or clinical practices from the last 5 years and think about how pharmacokinetic and pharmacodynamic factors altered his or her anticipated response to a drug.

· Consider factors that might have influenced the patient’s pharmacokinetic and pharmacodynamic processes, such as genetics (including pharmacogenetics), gender, ethnicity, age, behavior, and/or possible pathophysiological changes due to disease.

· Think about a personalized plan of care based on these influencing factors and patient history in your case study.


Rosenthal, L. D., & Burchum, J. R. (2018). Lehne’s pharmacotherapeutics for advanced practice providers. St. Louis, MO: Elsevier.

Chapter 1, “Prescriptive Authority” (pp. 1–3)
Chapter 2, “Rational Drug Selection and Prescription Writing” (pp. 5–9)
Chapter 3, “Promoting Positive Outcomes of Drug Therapy” (pp. 11–16)
Chapter 4, “Pharmacokinetics, Pharmacodynamics, and Drug Interactions” (pp. 17–40)
Chapter 5, “Adverse Drug Reactions and Medical Errors” (pp. 41–49)
Chapter 6, “Individual Variation in Drug Response” (pp. 51–56)

Fowler, M. D. M., & American Nurses Association. (2015). Guide to the Code of Ethics for Nurses with Interpretive Statements : Development, Interpretation, and Application: Vol. Second edition. American Nurses Association.

Shedding Light on Nurse Practitioner Prescribing

Ladd, Elissa; Hoyt, Alex.The Journal for Nurse Practitioners; Philadelphia Vol. 12, Iss. 3, (Mar 2016): 166-173. DOI:10.1016/j.nurpra.2015.09.017

Journal of the American Association of Nurse Practitioners May 2017, Volume 29 (5), p 248–254 © 2017 American Association of Nurse Practitioners

doi: 10.1002/2327-6924.12446 ISSN: 2327-6924

American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel*


Post a description of the patient case from your experiences, observations, and/or clinical practice from the last 5 years. Then, describe factors that might have influenced pharmacokinetic and pharmacodynamic processes of the patient you identified. Finally, explain details of the personalized plan of care that you would develop based on influencing factors and patient history in your case. Be specific and provide examples.

Supported by at least three current, credible sources. fully adheres to current APA manual writing rules and style. 1-2 pages

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