Applied Sciences

After reading Chapter 9 of Epidemiology for public health practice, complete Study Questions and Exercises 1–9. This activity is located on pages 431–432. Submit your responses in the form of a Word document.

1- Calculate the etiologic fraction when the RR for disease associated with a given exposure is 1.2, 1.8, 3, and 15.

2- The impact of an exposure on a population does not depend upon:

· a.the strength of the association between exposure and disease.

· b.the prevalence of the exposure.

· c.the case fatality rate.

· d.the overall incidence rate of disease in the population.

· The next seven questions (3–9) are based on the following data: The death rate per 100,000 for lung cancer is 7 among nonsmokers and 71 among smokers. The death rate per 100,000 for coronary thrombosis is 422 among nonsmokers and 599 among smokers. The prevalence of smoking in the population is 55%. (If necessary, refer to the chapter on cohort studies for formulas for RR.)

3- What is the RR of dying of lung cancer for smokers versus nonsmokers?

4-What is the RR of dying of coronary thrombosis for smokers versus nonsmokers?

5-What is the etiologic fraction of disease due to smoking among individuals with lung cancer?

6-What is the etiologic fraction of disease due to smoking among individuals with coronary thrombosis?

7-What is the population etiologic fraction of lung cancer due to smoking?

8-What is the population etiologic fraction of coronary thrombosis due to smoking?

9-On the basis of the RR and etiologic fractions associated with smoking from lung cancer and coronary thrombosis, which one of the following statements is most likely to be correct?

· Smoking seems much more likely to be causally related to coronary thrombosis than to lung cancer.

· b.Smoking seems much more likely to be causally related to lung cancer than to coronary thrombosis.

· c.Smoking seems to be equally causally related to both lung cancer and coronary thrombosis.

· d.Smoking does not seem to be causally related to either lung cancer or coronary thrombosis.

· e.No comparative statement is possible between smoking and lung cancer or coronary thrombosis.

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